Search results for " Affinity resin"
Article
A Look at the Affinity Chromatography Landscape
In addition to more base-tolerant resins, the selection of Protein A-based affinity resins has expanded to include resins with increased capacity and improved homogeneity of the chromatography beads, …
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A Closer Look at Affinity Ligands
Affinity ligands play an exciting role in the ever-growing sphere of downstream processing. In speaking with BioPharm International®, Phillip Elliott, PhD, associate director of Process Development,…
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Protein L affinity resin is ready to move to manufacturing
Although protein L affinity resins have been available for more than a decade, insufficient binding capacities and alkaline stability challenges have limited their use in productive manufactur…
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Efficient Cleaning-In-Place Methods for Protein-Based Antibody Affinity Chromatography Resins
As the use of sodium hydroxide (NaOH) is considered standard in the bioprocessing industry, the impact of treatment of affinity resins with various concentrations of this cleaning agent is demonstrate…
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Guide for selecting affinity resins for mAbs, bsAbs, and antibody fragments
Selecting an affinity resin for the diverse range of antibodies can be overwhelming. But don’t worry, in this selection guide you will find the antibody affinity resin to achieve your required purity …
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Webinar about a new affinity chromatography technology for recombinant proteins
Introducing new Cytiva™ Protein Select™ resin for recombinant protein purification in research and process development
On November 15, 2023, Cytiva announced the upcoming l…
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Production of recombinant proteins using a novel affinity technology
This scientific paper from Journal of Chromatography A describes results of a study utilizing a Cytiva Protein Select™ affinity resin and tag platform to produce any recombinant proteins.
Re…
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Bind, Cut, Elute — Easy Affinity Tag and Protease Removal
The tag is cleaved while the protein is still bound to the affinity resin.
Article
Re-use of Protein A Resin: Fouling and Economics
Mar 01, 2015
By Anurag S. Rathore, Mili Pathak, Guijun Ma, Daniel G. Bracewell
BioPharm International
Volume 3, Issue 28
In the past two decades, Protein A affinity chromatography ha…
Article
Process Chromatography: Continuous Optimization
In fact, according to Parra, highly selective affinity resins with antibody-like specificity can significantly improve a purification process making it simpler and more economical for a variety of mol…